In many clinical trials, training is conducted in face-to-face, live venues, typically at an Investigator Meeting or during a site initiation visit. Increasing pressure to manage study costs and the difficulty of convening in-person meetings for global trials are growing challenges. E-learning refers to any number of computer-based venues for delivering training. These can include interactive CD-ROM, video delivered by DVD or videotape, web-based self-paced training and web-based virtual meetings.