Adaptive Randomization

UBC’s automated randomization systems leverage the latest statistical techniques, programming technologies and validation procedures to integrate the adaptive algorithm and the randomization engine in a seamless and fully automated solution. Our methodology ensures that treatment groups are properly randomized without interruptions in the process and anticipates foreseeable randomization pitfalls that may compromise research.

Our systems provide the ability to:

  • Add or drop treatment arms seamlessly
  • Integrate the adaptive algorithm into the randomizing engine to eliminate any down time associated with loading a new randomization list
  • Implement a dynamic randomization scheme
  • Perform complex stratifications and balancing
  • Implement block randomizations
  • Randomize patients centrally
  • Use pre-programmed un-blinding mechanisms